Repurposed Drug Database


Idoxuridine

Original Indication
Treatment of keratitis caused by the virus of herpes simplex.
New Indication
Treatment of nonparenchymatous sarcomas.

Imciromab pentetate

Original Indication
A cardiac imaging agent for detecting the presence and location of myocardial injury in patients with suspected myocardial infarction.
New Indication
Detecting early necrosis as an indication of rejection of orthotopic cardiac transplants.

Interferon beta-1a (recombinant human)

Original Indication
Treatment of relapsing forms of multiple sclerosis to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations.
New Indication
For the systemic treatment of cutaneous T-cell lymphoma.

Interferon beta 1b (recombinant)

Original Indication
In ambulatory patients with relapsing-remitting multiple sclerosis to reduce the frequency of clinical exacerbations.
New Indication
Treatment of acquired immunodeficiency syndrome.

Idarubicin

Original Indication
Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.
New Indication
Treatment of acute lymphoblastic leukemia in pediatric patients.

Ifosfamide

Original Indication
In combination with certain other approved antineoplastic agents, for third line chemotherapy in the treatment of germ cell testicular cancer.
New Indication
Treatment of bone sarcomas.

Iloprost solution for infusion

Original Indication
Treatment of pulmonary arterial hypertension (WHO Group I) in patients with NYHA Class III or IV symptoms.
New Indication
Treatment of Raynaud's phenomenon secondary to systemic sclerosis.

Interferon gamma-1b

Original Indication
Actimmune is indicated for delaying time to disease progression in patients with severe, malignant osteopetrosis.
New Indication
Treatment of idiopathic pulmonary fibrosis.

Immuneglobulin Intravenous (Human)

Original Indication
For prophylaxis of children with clinical or immunologic evidence of human immunodeficiency virus to decrease the frequency of serious and minor bacterial infections and the frequency of hospitalization, and to increase the time free of serious bacterial infection.
New Indication
Treatment of juvenile rheumatoid arthritis.

Infliximab

Original Indication
Treatment of moderately to severely active Crohn's disease for the reduction of the signs and symptoms, in patients who have an inadequate response to conventional therapies; and treatment of patients with fistulizing Crohn's disease for the reduction in the number of draining enterocutaneous fistula(s).
New Indication
Treatment of juvenile rheumatoid arthritis.

Interferon alfa-2a (recombinant)

Original Indication
Roferon-A is indicated for chronic phase, Philadelphia chromosome positive chronic myelogenous leukemia patients who are minimally pretreated (within 1 year of diagnosis).
New Indication
For use in combination with fluorouracil for the treatment of esophageal carcinoma.

Interferon alfa-2b (recombinant)

Original Indication
INTRON A is indicated for the treatment of selected patients 18 years of age or older with AIDS-Related Kaposi's Sarcoma.
New Indication
Treatment of chronic myelogenous leukemia.

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