Repurposed Drug Database


Ropinirole

Original Indication
Hypertension.
New Indication
Restless leg syndrome.

Raloxifene

Original Indication
Osteoporosis.
New Indication
Breast and prostate cancer.

Rapamycin (mTOR) inhibitor

Original Indication
Sirolimus is an immunosuppressive agent indicated for the prophylaxis of organ rejection in patients aged 13 years receiving renal transplants.
New Indication
Treatment of tuberous sclerosis complex.

Recombinant human C1 inhibitor

Original Indication
Berinert is a plasma-derived C1 Esterase Inhibitor (Human) indicated for the treatment of acute abdominal or facial attacks of hereditary angioedema in adult and adolescent patients.
New Indication
Prevention and/or treatment of delayed graft function after solid organ transplantation.

Repository corticotropin or adrenocorticotropic hormone

Original Indication
Corticotropin is indicated for treatment of acute exacerbations of multiple sclerosis.
New Indication
Treatment of infantile spasms.

Rifabutin

Original Indication
Prevention of disseminated Mycobacterium avium complex disease in patients with advanced HIV infections.
New Indication
Treatment of disseminated Mycobacterium avium complex disease.

Riluzole

Original Indication
Treatment of patients with amyotrophic lateral sclerosis.
New Indication
Treatment of Huntington's disease.

Rabbit anti-human thymocyte globulin (rATG)

Original Indication
Treatment of renal transplant acute rejection in conjunction with concomitant immunosuppression.
New Indication
Treatment of myelodysplastic syndrome.

Risedronate sodium

Original Indication
1.Treatment and prevention of postmenopausal osteoporosis; 2.Treatment to increase bone mass in men with osteoporosis; 3.Treatment and prevention of glucocorticoid-induced osteoporosis; 4.Treatment of Paget s disease.
New Indication
Treatment of patients with osteogenesis imperfecta.

Ribavirin

Original Indication
Ribavirin tablets in combination with peginterferon alfa-2a are indicated for the treatment of adults with chronic hepatitis C virus infection who have compensated liver disease and have not been previously treated with interferon alpha.
New Indication
Treatment of hemorrhagic fever with renal syndrome.

Rituximab

Original Indication
Treatment of patients with:1. Non-Hodgkin s Lymphoma. 2. Chronic Lymphocytic Leukemia.
New Indication
Treatment of immune thrombocytopenic purpura.

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