Repurposed Drug Database


Urofollitropin

Original Indication
Bravelle administered SC or IM in conjunction with hCG, is indicated for: 1.ovulation induction in patients; 2. multiple follicular development (controlled ovarian stimulation) during ART cycles, in patients who have previously received pituitary suppression.
New Indication
For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism.

Ursodiol

Original Indication
1. Ursodiol is indicated for patients with radiolucent, noncalcified gallbladder stones < 20 mm in greatest diameter in whom elective cholecystectomy would be undertaken except for the presence of increased surgical risk due to systemic disease, advanced age, idiosyncratic reaction to general anesthesia, or for those patients who refuse surgery. 2.Ursodiol is indicated for the prevention of gallstone formation in obese patients experiencing rapid weight loss.
New Indication
Treatment of cystic fibrosis liver disease.

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